Author Archives: karen

Link: Interactions of Sen1/Nrd1/Nab3 with Multiple Phosphorylated Forms of the Rpb1 C-terminal Domain in Saccharomyces cerevisiae. Chinchilla K, Rodriguez-Molina J, Ursic D, Finkel JS, Ansari AZ, Culbertson MR. Laboratory of Genetics. The Saccharomyces cerevisiae SEN1 gene codes for a nuclear, ATP-dependent helicase which is embedded in a complex network of protein-protein interactions. Pleiotropic phenotypes of mutations in SEN1 suggest that Sen1 … Continue reading »

Link: Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases. Kuny CV, Chinchilla K, Culbertson MR, Kalejta RF. Institute for Molecular Virology and McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin, United States of America. The UL97 protein of human cytomegalovirus (HCMV, or HHV-5 (human herpesvirus 5)), is a … Continue reading »

Link: Sen1p performs two genetically separable functions in transcription and processing of U5 small nuclear RNA in Saccharomyces cerevisiae Finkel JS, Chinchilla K, Ursic D, Culbertson MR. Laboratories of Genetics and Molecular Biology, University of Wisconsin, Madison, Wisconsin 53706, USA. The Saccharomyces cerevisiae SEN1 gene codes for a nuclear-localized superfamily I helicase. SEN1 is an ortholog … Continue reading »

Link: Multiple protein/protein and protein/RNA interactions suggest roles for yeast DNA/RNA helicase Sen1p in transcription, transcription-coupled DNA repair and RNA processing   Ursic D, Chinchilla K, Finkel JS, Culbertson MR. Laboratories of Molecular Biology and Genetics, R.M. Bock Laboratories, 1525 Linden Drive, University of Wisconsin, Madison, WI 53706, USA. Sen1p in Saccharomyces cerevisiae is a Type … Continue reading »